Acarbosa - Dosage, Indications and Contraindications

Acarbosa - Dosage, Indications and Contraindications

Acarbosa Drug AZ

Name:Acarbosa

Group: antidiabetic, alpha-glucosidase inhibitors
Trademarks: Precose
Available in tablet form: 25 mg, 5 mg, 100mg

Dosage and Indication
For Type 2 Diabetes:

• Initial dose: 25 mg taken orally every 8 hours when eating (the first bite of food eaten and drunk drugs)
• The dose can be increased to 50 or 100 mg orally every 8 hours with a distance of 4-8 weeks based on the value of sugar 1 hour after eating or glycosylated hemoglobin levels (HbA1c), or the oral glucose tolerance test value per physician

The maximum dose:

• Patients with body weight <60 kg: 50 mg every 8 hours
• Patients with body weight> 60 kg: 100 mg every 8 hours

Usage:
For diabetes mellitus type 2, a single therapy or in combination with sulfonylurea treatment

Side Effects
With a frequency of> 10%

• Abdominal pain (19%)
• Diarrhea (31%)
• Increased serum transaminases
• Fart (74%)

The report, obtained after the drug was marketed:

• Gastrointestinal: fulminant hepatitis with fatal outcome, ileus / subileus (disorders of the small intestine peristalsis), jaundice and / or hepatitis, and hepatic disorders related
• Skin hypersensitivity reactions: rash, erythema, exanthema and urticaria
• Edema
• thrombocytopenia
• Pneumatosis cystoides intestinalis

contraindications

• Recorded history of hypersensitivity (allergy) to acarbosa
• Diabetic ketoacidosis, cirrhosis, inflammatory bowel disease, colonic ulceration, partial intestinal blockage or partial blockage risk, impaired absorption in the gastrointestinal tract

WARNING

• There are no clinical studies on evidence of macrovascular risk reduction in the acarbosa or other antidiabetic drugs
• Concomitant use with sulfonylureas or insulin berisikko hypoglycemic events;handle hypoglycemia with an oral glucose (dextrose) and sucrose do

Pregnancy and Breastfeeding
Security for Pregnancy: Category B.
Type category of drugs for pregnancy:

• Category A: It is generally accepted, has been through research on pregnant women, and shows no evidence of damage to the fetus
• Category B: It may be acceptable to pregnant women, have gone through animal studies but there is no direct evidence in human studies.
• Category C: Used with caution.Animal studies indicate the risk and there is no direct human studies on
• Category D: Used if no other drugs that can be used, and in a life-threatening condition.
• Category X: Do not use in pregnancy.
• Category NA: No information

Not recommended in nursing mothers because no data on whether the drug enters breast milk or not.

Creator Unknown On 05:44